Cellular Localization and Trafficking of the Human ABCG1 Transporter
نویسندگان
چکیده
منابع مشابه
Cellular Localization and Trafficking of the Human ABCG1 Transporter
We have developed a suitable heterologous cell expression system to study the localization, trafficking, and site(s) of function of the human ABCG1 transporter. Increased plasma membrane (PM) and late endosomal (LE) cholesterol generated by ABCG1 was removed by lipoproteins and liposomes, but not apoA-I. Delivery of ABCG1 to the PM and LE was required for ABCG1-mediated cellular cholesterol eff...
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ژورنال
عنوان ژورنال: Biology
سال: 2014
ISSN: 2079-7737
DOI: 10.3390/biology3040781